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Michael Kluge Selected Research

APG101

1/2018Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma.
1/2013Recombinant CD95-Fc (APG101) prevents graft-versus-host disease in mice without disabling antitumor cytotoxicity and T-cell functions.

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Michael Kluge Research Topics

Disease

11Neoplasms (Cancer)
01/2021 - 06/2010
10Schizophrenia (Dementia Praecox)
01/2022 - 03/2007
3Psychotic Disorders (Schizoaffective Disorder)
01/2022 - 12/2007
3Pancreatic Neoplasms (Pancreatic Cancer)
12/2019 - 01/2018
3Weight Gain
04/2013 - 12/2007
2Glioblastoma (Glioblastoma Multiforme)
04/2019 - 01/2018
2Mania (Manias)
01/2018 - 02/2013
2Weight Loss (Weight Reduction)
06/2012 - 07/2008
2Body Weight (Weight, Body)
06/2012 - 07/2008
2Sleepiness
06/2012 - 03/2012
2Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
12/2007 - 10/2006
1Encephalitis (Encephalitis, Rasmussen)
01/2022
1Mood Disorders (Mood Disorder)
01/2022
1Leukocytosis (Pleocytosis)
01/2022
1Borderline Personality Disorder (Personality Disorders, Borderline)
01/2021
1Squamous Cell Carcinoma of Head and Neck
01/2021
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021
1Demyelinating Diseases (Demyelinating Disease)
01/2021
1Infections
01/2021
1Colorectal Neoplasms (Colorectal Cancer)
01/2021
1Tobacco Use Disorder (Nicotine Dependence)
12/2020
1Hypopituitarism (Sheehan's Syndrome)
10/2020
1Brain Neoplasms (Brain Tumor)
04/2019
1Treatment-Resistant Schizophrenia
01/2019
1Neoplasm Metastasis (Metastasis)
01/2018
1Glioma (Gliomas)
01/2018
1Adenocarcinoma
01/2018
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/2018
1Leukemia
10/2017
1Dementia (Dementias)
02/2015
1Feeding and Eating Disorders (Eating Disorder)
02/2015
1Overweight
02/2015
1Mental Disorders (Mental Disorder)
02/2015
1Restless Legs Syndrome (Restless Legs)
01/2014
1Sleep Deprivation
06/2013
1B-Cell Leukemia (Leukemia, B Cell)
01/2013

Drug/Important Bio-Agent (IBA)

9Antipsychotic Agents (Antipsychotics)IBA
01/2022 - 03/2007
7Olanzapine (Zyprexa)FDA Link
01/2022 - 12/2007
5GhrelinIBA
01/2022 - 06/2012
4RNA (Ribonucleic Acid)IBA
01/2021 - 11/2019
4Clozapine (Clozaril)FDA LinkGeneric
01/2014 - 12/2007
3LigandsIBA
01/2021 - 01/2018
3Proteins (Proteins, Gene)FDA Link
01/2021 - 10/2017
3Pharmaceutical PreparationsIBA
12/2020 - 04/2007
2Amisulpride (Solian)IBA
01/2022 - 02/2020
2LeptinIBA
01/2022 - 07/2008
2CytokinesIBA
01/2021 - 01/2009
2APG101IBA
01/2018 - 01/2013
2APG350IBA
01/2018 - 12/2013
2Methylphenidate (Ritalin)FDA LinkGeneric
01/2018 - 02/2013
1N-Methylaspartate (NMDA)IBA
01/2022
1AdiponectinIBA
01/2022
1AutoantibodiesIBA
01/2022
1AdipokinesIBA
01/2022
1histone H3 trimethyl Lys4IBA
01/2021
12-5A-dependent ribonuclease (RNase L)IBA
01/2021
1Chimeric Antigen ReceptorsIBA
01/2021
1Tyrosine Kinase InhibitorsIBA
01/2021
1ActomyosinIBA
01/2021
1Monoclonal AntibodiesIBA
01/2021
1EnzymesIBA
01/2021
1Epidermal Growth Factor (EGF)IBA
01/2021
1Immunoglobulin G (IgG)IBA
01/2021
1Immunoglobulin Fc FragmentsIBA
01/2021
1ImmunosorbentsIBA
01/2021
1Phosphates (Orthophosphate)IBA
01/2021
1Small Nuclear RNA (snRNA)IBA
01/2021
1IntegrinsIBA
01/2021
1Myelin-Oligodendrocyte GlycoproteinIBA
01/2021
1ErbB Receptors (EGF Receptor)IBA
01/2021
1Peptide Hormones (Polypeptide Hormones)IBA
12/2020
1Hormones (Hormone)IBA
10/2020
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
11/2019
1Poly I-CIBA
11/2019
1OvalbuminIBA
11/2019
1Interferon Type IIBA
11/2019
1RNA Polymerase II (RNA Polymerase B)IBA
01/2019
1CannabidiolIBA
01/2019
1Phosphotransferases (Kinase)IBA
01/2019
1Death Domain ReceptorsIBA
01/2018
1Matrix Metalloproteinases (MMPs)IBA
01/2018
1Fas Ligand Protein (Fas Ligand)IBA
01/2018
1navitoclaxIBA
01/2018
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2018
1Metalloproteases (Metalloproteinases)IBA
01/2018
1Antimanic AgentsIBA
01/2018
1Positive Transcriptional Elongation Factor BIBA
10/2017
1Antidepressive Agents (Antidepressants)IBA
02/2015
1Quetiapine Fumarate (Seroquel)FDA Link
04/2013
1CarbohydratesIBA
04/2013

Therapy/Procedure

6Therapeutics
01/2021 - 06/2012
1Immunotherapy
11/2019
1Palliative Care (Palliative Therapy)
01/2018
1Radiotherapy
01/2018
1Heterologous Transplantation (Xenotransplantation)
01/2018
1Art Therapy
06/2013
1Drug Therapy (Chemotherapy)
06/2013
1Occupational Therapy (Therapy, Occupational)
06/2013
1Phototherapy (Light Therapy)
06/2013
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
01/2013